Process Analytics for the Pharmaceutical Industry

Accurate and reliable liquid analytics are critical to maintaining compliance, ensuring product safety, and optimizing production efficiency in pharmaceutical manufacturing. M4 Knick delivers precise pH, conductivity, and dissolved oxygen measurement solutions designed to meet rigorous regulatory standards and enhance operational effectiveness.

Process Analytics for the Pharma Industry

Accurate and reliable measurements are critical to maintaining compliance, ensuring product safety, & optimizing efficiency in pharmaceutical manufacturing. We deliver precise pH, conductivity and dissolved oxygen measurement solutions that meet regulatory standards and enhance operational effectiveness.

Overcoming Challenges in Pharmaceutical Manufacturing

Reducing Contamination and Batch Loss

Maintaining sterile conditions is essential in pharmaceutical manufacturing, where contamination can lead to costly batch loss and regulatory consequences. Manual interventions introduce risk and disrupt the integrity of closed-loop systems.
Knick’s automated sensor cleaning and calibration systems minimize human interaction, supporting aseptic processes and helping facilities maintain a closed system. This reduces contamination events, safeguards product integrity, and preserves valuable production batches.
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Increasing Throughput by Reducing Downtime

Manual sensor maintenance and process delays extend turnaround times and reduce overall throughput. In high-volume pharmaceutical manufacturing, every minute counts.
By automating sensor maintenance, automated systems accelerate turnaround, reduce manual workload, and keep production moving. This increases uptime and supports lean manufacturing goals without compromising measurement reliability.
AUTO CLEANING & CAL OPTIONS

Ensuring Repeatable, Accurate Calibrations

Inconsistent pH readings can push final product quality out of specification, leading to rework or even discarded batches. Manual calibration methods are prone to variability and documentation challenges.
Knick Memosens digital sensors ensure highly repeatable calibrations with stored sensor history and diagnostics. This improves confidence in every reading, supports regulatory audits, and helps reduce the chance of final product deviation.
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Equipment Designed for Pharma Requirements

Lab & Process Measurement Solutions

In pharmaceutical manufacturing, lab and process teams rely on consistent, traceable measurements to ensure product quality and meet compliance standards. Lab verification is often essential for batch release, while process sensors support real-time adjustments.

Memosens technology can also benefit the lab:

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Sensor documentation with performance history

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Direct printing of calibration reports for compliance

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Standardize your measurement technologies in the lab and the field

Application Examples

CIP & SIP Conductivity Measurements

Unreliable measurements can cause downtime or even worse, contaminated batches due to leftover product or detergents.
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Permitted Outfall: Automating pH Measurements in the Pharma Industry

In a pharmaceutical plant, there are multiple steps in treating wastewater created during drug manufacturing.
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Bio-Fermentation in the Pharmaceutical Industry

Fermentation, or 'bio-fermentation' in the pharmaceutical industry, refers to the process of harvesting pharmaceutical, therapeutic material from biologic material.
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Conductivity Measurements in Water for Injection (WFI)

Conductivity measurements in WFI are essential for assessing purity, monitoring system performance, validating purification methods, and preventing microbial growth.
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pH Measurement in Chromatography

Chromatography is a method in biophysical and pharmaceutical applications that enables the separation, identification, and purification of molecules in a mixture based on their different properties.
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Automating Buffer Preparation for the Pharmaceutical Industry

As with any bio-tech process, the margin for error in buffer preparation is scarce. Improper pH levels can dilute the extracted molecule and decrease process yield.
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Pharmaceutical Industry